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Regarding preclinical studies, there are several unexplored research opportunities for experimental animal studies using, for example, (1) chronic short sleep duration or chronic sleep fragmentation models, (2) circadian misalignment/jetlag models including a urolithin A intervention arm, and (3) germ-free mice or fecal matter transplant to investigate whether the effects of urolithin A are dependent on the microbiota

When your skin feels reactive, itchy, or uncomfortable, it often points to deeper processes happening inside the body

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For instance, caffeine is an adenosine blocker, which prevents adenosine from binding to its receptors that help make you sleepy